A battery of image-based biomarkers or signatures are inserted into Supervised Target Detection Algorithms and applied to the tumor. The highest Gleason score at a pixel is determined and recorded
Here is an example showing various Gleason Scores inside the tumor
Prostate displayed as color where red is kep green is DWI-High B blue is ADC b. Gleason scoring inside tumor using Maximum SAM with Whitened-DeWhitened signatures c. Gleason Scoring Weighted SAM using Whitened-DeWhitened signatures
Advanced Algorithm and Image-Based Biomarkers for Cancer Detection, Scoring and Tumor Volume Measurements and Color Display
